Linked Life Data

21052539

Source:http://linkedlifedata.com/resource/pubmed/id/21052539

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-11-5
pubmed:abstractText
IL-12 is a cytokine with links to both innate and adaptive immunity systems. In mice, its deletion leads to acute susceptibility to oral infection with the yeast Candida albicans, whereas such mice are resistant to systemic disease. However, it is an essential component of the adaptive response that leads to the generation of Th1-type cytokine responses and protection against disseminated disease. This paper presents an overview of the role of IL-12 in models of systemic and mucosal infection and the possible relationships between them.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1740-2530
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
2011
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
686597
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
IL-12 and related cytokines: function and regulatory implications in Candida albicans infection.
pubmed:affiliation
The School of Dentistry, University of Queensland School of Dentistry, 200 Turbot Street, Brisbane, QLD 4000, Australia. r.ashman@uq.edu.au
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't