Human papillomavirus (HPV) type 16 is the major etiological agents of cervical cancer. Recently, the studies have demonstrated that HPV intratypic variations could affect oncogenic potential to cervical cancer development. The objectives of this study were to identify HPV-16 E6 and E7 variants prevalent in Chinese women and to assess the risk of them for invasive cervical carcinoma and cervical intraepithelial neoplasia (CIN).
Women's Reproductive Health Key Laboratory of Zhejiang Province, and Women's Hospital, School of Medicine, Zhejiang University, Xueshi Road #2, Hangzhou, China.
