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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-10-20
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pubmed:abstractText |
Transcription factors act as molecular switches to activate or repress specific genes, which in turn control cellular phenotype. Transcription factor OCT4 is critical for self-renewal and maintenance of embryonic stem cells. OCT4 expression is down-regulated in all differentiated somatic cell types in vitro and in vivo. Our aim is to investigate whether the human corneal epithelium expresses OCT4.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1460-2202
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
978-85
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pubmed:dateRevised |
2011-2-22
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pubmed:meshHeading |
pubmed-meshheading:20958186-Adult,
pubmed-meshheading:20958186-Aged,
pubmed-meshheading:20958186-Biological Markers,
pubmed-meshheading:20958186-Child,
pubmed-meshheading:20958186-Child, Preschool,
pubmed-meshheading:20958186-Embryonic Stem Cells,
pubmed-meshheading:20958186-Epithelium, Corneal,
pubmed-meshheading:20958186-Female,
pubmed-meshheading:20958186-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:20958186-Humans,
pubmed-meshheading:20958186-Male,
pubmed-meshheading:20958186-Middle Aged,
pubmed-meshheading:20958186-Octamer Transcription Factor-3,
pubmed-meshheading:20958186-RNA, Messenger,
pubmed-meshheading:20958186-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2010
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pubmed:articleTitle |
Human corneal basal epithelial cells express an embryonic stem cell marker OCT4.
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pubmed:affiliation |
Zhongshan Ophthalmic Center, The State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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