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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2011-1-21
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pubmed:abstractText |
The transcription factor TCF21 is involved in mesenchymal-to-epithelial differentiation and was shown to be aberrantly hypermethylated in lung and head and neck cancers. Because of its reported high frequency of hypermethylation in lung cancer, further characterization of the stages and types of nonsmall cell lung cancer (NSCLC) that are hypermethylated and the frequency of hypermethylation and associated "second hits" were assessed.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-543X
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pubmed:author |
pubmed-author:BachinskiLinda LLL,
pubmed-author:BaggerlyKeith AKA,
pubmed-author:ChurchillJenniferJ,
pubmed-author:DongWenliW,
pubmed-author:HayesD NeilDN,
pubmed-author:KraheRalfR,
pubmed-author:RichardsKristy LKL,
pubmed-author:SunMenghongM,
pubmed-author:WilsonCharmaine DCD,
pubmed-author:WistubaIgnacio III,
pubmed-author:YinGuoshengG,
pubmed-author:ZhangBailiB
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pubmed:copyrightInfo |
Copyright © 2010 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
606-17
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pubmed:meshHeading |
pubmed-meshheading:20945327-Basic Helix-Loop-Helix Transcription Factors,
pubmed-meshheading:20945327-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20945327-DNA Methylation,
pubmed-meshheading:20945327-Down-Regulation,
pubmed-meshheading:20945327-Female,
pubmed-meshheading:20945327-Humans,
pubmed-meshheading:20945327-Immunohistochemistry,
pubmed-meshheading:20945327-Lung Neoplasms,
pubmed-meshheading:20945327-Male,
pubmed-meshheading:20945327-Promoter Regions, Genetic,
pubmed-meshheading:20945327-Tumor Markers, Biological
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pubmed:year |
2011
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pubmed:articleTitle |
Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers.
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pubmed:affiliation |
Department of Genetics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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