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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-12-24
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pubmed:abstractText |
INTRODUATION: Resveratrol, a phytoestrogen present at a high concentration in red wine, has been reported to possess many health benefit effects that are protective against age-related diseases. Protein S (PS), an important anticoagulant factor in the protein C (PC) anticoagulant pathway, is mainly synthesized by hepatocytes, and its plasma level is decreased in high-estrogen conditions such as pregnancy and oral contraceptive use. The aim of this study was to investigate whether resveratrol affects PS expression in HepG2 cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3,3',4,5'-tetrahydroxystilbene,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/C4BPB protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Estrogen Receptor alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Genistein,
http://linkedlifedata.com/resource/pubmed/chemical/Histocompatibility Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/PROS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Phytoestrogens,
http://linkedlifedata.com/resource/pubmed/chemical/Protein C,
http://linkedlifedata.com/resource/pubmed/chemical/Protein S,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Stilbenes,
http://linkedlifedata.com/resource/pubmed/chemical/resveratrol
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1879-2472
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e1-7
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pubmed:meshHeading |
pubmed-meshheading:20926118-Blood Proteins,
pubmed-meshheading:20926118-Blotting, Western,
pubmed-meshheading:20926118-Carcinoma, Hepatocellular,
pubmed-meshheading:20926118-Dose-Response Relationship, Drug,
pubmed-meshheading:20926118-Down-Regulation,
pubmed-meshheading:20926118-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20926118-Estrogen Receptor alpha,
pubmed-meshheading:20926118-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20926118-Genistein,
pubmed-meshheading:20926118-Hep G2 Cells,
pubmed-meshheading:20926118-Histocompatibility Antigens,
pubmed-meshheading:20926118-Humans,
pubmed-meshheading:20926118-Liver Neoplasms,
pubmed-meshheading:20926118-Molecular Structure,
pubmed-meshheading:20926118-Phytoestrogens,
pubmed-meshheading:20926118-Promoter Regions, Genetic,
pubmed-meshheading:20926118-Protein C,
pubmed-meshheading:20926118-Protein S,
pubmed-meshheading:20926118-RNA, Messenger,
pubmed-meshheading:20926118-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20926118-Stilbenes,
pubmed-meshheading:20926118-Structure-Activity Relationship,
pubmed-meshheading:20926118-Time Factors,
pubmed-meshheading:20926118-Transcription, Genetic,
pubmed-meshheading:20926118-Transfection,
pubmed-meshheading:20926118-Wine
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pubmed:year |
2011
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pubmed:articleTitle |
Resveratrol, a phytoestrogen found in red wine, down-regulates protein S expression in HepG2 cells.
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pubmed:affiliation |
Graduate School of Health and Nutrition Sciences, Nakamura Gakuen University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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