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pubmed-article:20888389pubmed:abstractTextSuppression of normal hematopoiesis by the neoplastic clone (clonal dominance) is a feature of the myeloproliferative neoplasms, but the determinants that predict clonal dominance are unknown. The objective of this study was to identify clinical and laboratory variables that associate with the JAK2 V617F CD34(+) progenitor allele burden and clonal dominance, which was defined by congruence of the JAK2 V617F CD34(+) progenitor and neutrophil allele burdens.lld:pubmed
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pubmed-article:20888389pubmed:copyrightInfoCopyright © 2011 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.lld:pubmed
pubmed-article:20888389pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20888389pubmed:volume39lld:pubmed
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pubmed-article:20888389pubmed:pagination95-101lld:pubmed
pubmed-article:20888389pubmed:dateRevised2011-9-26lld:pubmed
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pubmed-article:20888389pubmed:articleTitleDisease burden at the progenitor level is a feature of primary myelofibrosis: a multivariable analysis of 164 JAK2 V617F-positive myeloproliferative neoplasm patients.lld:pubmed
pubmed-article:20888389pubmed:affiliationNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.lld:pubmed
pubmed-article:20888389pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20888389pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
pubmed-article:20888389pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed
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