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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2010-9-23
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pubmed:abstractText |
Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease of cattle. The bovine prion gene (PRNP) contains regions of both high and low linkage disequilibrium (LD) that appear to be conserved across Bos taurus populations. The region of high LD, which spans the promoter and part of intron 2, contains polymorphic loci that have been associated with classical BSE status. However, the complex genetic architecture of PRNP has not been systematically tested for an association with classical BSE.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:meshHeading |
pubmed-meshheading:20862290-Animals,
pubmed-meshheading:20862290-Base Sequence,
pubmed-meshheading:20862290-Cattle,
pubmed-meshheading:20862290-Encephalopathy, Bovine Spongiform,
pubmed-meshheading:20862290-Europe,
pubmed-meshheading:20862290-Haplotypes,
pubmed-meshheading:20862290-Incidence,
pubmed-meshheading:20862290-Molecular Sequence Data,
pubmed-meshheading:20862290-Polymorphism, Single Nucleotide,
pubmed-meshheading:20862290-Prions
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pubmed:year |
2010
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pubmed:articleTitle |
PRNP haplotype associated with classical BSE incidence in European Holstein cattle.
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pubmed:affiliation |
Department of Agricultural, Food and Nutritional Science, University of Alberta, Alberta, Edmonton, Canada. bmurdoch@ualberta.ca
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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