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rdf:type |
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lifeskim:mentions |
umls-concept:C0006400,
umls-concept:C0007876,
umls-concept:C0036082,
umls-concept:C0038585,
umls-concept:C0085295,
umls-concept:C0184959,
umls-concept:C0332803,
umls-concept:C0392756,
umls-concept:C0442805,
umls-concept:C0443315,
umls-concept:C0549178,
umls-concept:C1707455
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pubmed:issue |
6
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pubmed:dateCreated |
2010-11-25
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pubmed:abstractText |
Recent evidence suggests that locally delivered local anesthetics may exert tissue-damaging effects such as chondrolysis after intraarticular injection. Alteration of the inflammatory response is a potential mechanism for local anesthetic-induced tissue toxicity. In this study, we tested the effects of continuous local anesthetic infiltration on the release of inflammatory and nociceptive mediators in skin wounds after cesarean delivery.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Local,
http://linkedlifedata.com/resource/pubmed/chemical/Bupivacaine,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/IL10 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/NGF protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Chloride,
http://linkedlifedata.com/resource/pubmed/chemical/Substance P
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1526-7598
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1452-9
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pubmed:dateRevised |
2011-3-29
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pubmed:meshHeading |
pubmed-meshheading:20861424-Adult,
pubmed-meshheading:20861424-Analgesia, Obstetrical,
pubmed-meshheading:20861424-Anesthetics, Local,
pubmed-meshheading:20861424-Bupivacaine,
pubmed-meshheading:20861424-California,
pubmed-meshheading:20861424-Cesarean Section,
pubmed-meshheading:20861424-Dinoprostone,
pubmed-meshheading:20861424-Down-Regulation,
pubmed-meshheading:20861424-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20861424-Exudates and Transudates,
pubmed-meshheading:20861424-Female,
pubmed-meshheading:20861424-Humans,
pubmed-meshheading:20861424-Inflammation Mediators,
pubmed-meshheading:20861424-Infusions, Subcutaneous,
pubmed-meshheading:20861424-Interleukin-10,
pubmed-meshheading:20861424-Nerve Growth Factor,
pubmed-meshheading:20861424-Pain, Postoperative,
pubmed-meshheading:20861424-Pain Measurement,
pubmed-meshheading:20861424-Pregnancy,
pubmed-meshheading:20861424-Sodium Chloride,
pubmed-meshheading:20861424-Subcutaneous Tissue,
pubmed-meshheading:20861424-Substance P,
pubmed-meshheading:20861424-Surgical Procedures, Elective,
pubmed-meshheading:20861424-Time Factors,
pubmed-meshheading:20861424-Treatment Outcome,
pubmed-meshheading:20861424-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Continuous subcutaneous instillation of bupivacaine compared to saline reduces interleukin 10 and increases substance P in surgical wounds after cesarean delivery.
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pubmed:affiliation |
Department of Anesthesia, H3580, Stanford University School of Medicine, Stanford, CA 94305, USA. bcarvalho@stanford.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, N.I.H., Extramural
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