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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-11-5
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pubmed:abstractText |
Several randomized controlled trials have shown that pharmacological thromboprophylaxis with low-dose unfractionated heparin (UFH), low molecular weight heparin (LMWH) or fondaparinux reduces venous thromboembolism (VTE) after general surgery. No high-quality evidence supports the use of pharmacological thromboprohylaxis with traditional antithrombotic drugs in patients undergoing ambulatory surgery without additional VTE risk factors, stratified at low risk of VTE by the American College of Chest Physicians guidelines. Two new drug classes, the direct thrombin and factor Xa (FXa) inhibitors, have been developed with a potentially better risk-benefit profile.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1473-6500
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
722-5
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pubmed:meshHeading |
pubmed-meshheading:20847691-Administration, Oral,
pubmed-meshheading:20847691-Ambulatory Surgical Procedures,
pubmed-meshheading:20847691-Anticoagulants,
pubmed-meshheading:20847691-Factor Xa,
pubmed-meshheading:20847691-Heparin,
pubmed-meshheading:20847691-Heparin, Low-Molecular-Weight,
pubmed-meshheading:20847691-Humans,
pubmed-meshheading:20847691-Polysaccharides,
pubmed-meshheading:20847691-Premedication,
pubmed-meshheading:20847691-Randomized Controlled Trials as Topic,
pubmed-meshheading:20847691-Risk Assessment,
pubmed-meshheading:20847691-Thrombin,
pubmed-meshheading:20847691-Venous Thromboembolism
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pubmed:year |
2010
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pubmed:articleTitle |
The new oral anticoagulants, do they change the benefit vs. risk for thromboprophylaxis in association to ambulatory surgery?
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pubmed:affiliation |
Research Center on Thromboembolic Disorders and on Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy. alexsquizzo@libero.it
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pubmed:publicationType |
Journal Article,
Review
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