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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-12-3
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pubmed:abstractText |
Esophageal squamous cell cancer accounts for more than 90% of cases of esophageal cancers. Its pathogenesis involves chronic epithelial irritation, although the factors involved in the inflammatory process and the mechanisms of carcinogenesis are unknown. We sought to develop a mouse model of this cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2124-2134.e9
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pubmed:meshHeading |
pubmed-meshheading:20816834-Animals,
pubmed-meshheading:20816834-Carcinoma, Squamous Cell,
pubmed-meshheading:20816834-Cell Transformation, Neoplastic,
pubmed-meshheading:20816834-Cells, Cultured,
pubmed-meshheading:20816834-Disease Models, Animal,
pubmed-meshheading:20816834-Epithelial Cells,
pubmed-meshheading:20816834-Esophageal Neoplasms,
pubmed-meshheading:20816834-Esophagitis,
pubmed-meshheading:20816834-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20816834-Kruppel-Like Transcription Factors,
pubmed-meshheading:20816834-Mice,
pubmed-meshheading:20816834-Mice, Inbred C57BL,
pubmed-meshheading:20816834-Mice, Mutant Strains
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pubmed:year |
2010
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pubmed:articleTitle |
Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice.
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pubmed:affiliation |
Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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