Linked Life Data

20730162

Source:http://linkedlifedata.com/resource/pubmed/id/20730162

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
37
pubmed:dateCreated
2010-9-8
pubmed:abstractText
Copper enhances amyloid cytotoxicity and mediates human islet amyloid polypeptide (hIAPP) oligomerization; nickel, a redox inactive metal with similar protein binding affinity to copper, also mimics this effect, thereby demonstrating copper-mediated hIAPP cytotoxicity is due mainly to granular oligomer generation rather than ROS accumulation in type 2 diabetes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1364-548X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
7
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6909-11
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Copper-induced cytotoxicity: reactive oxygen species or islet amyloid polypeptide oligomer formation.
pubmed:affiliation
The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't