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rdf:type |
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lifeskim:mentions |
umls-concept:C0009566,
umls-concept:C0011860,
umls-concept:C0017337,
umls-concept:C0027893,
umls-concept:C0030705,
umls-concept:C0037081,
umls-concept:C0205217,
umls-concept:C0332152,
umls-concept:C0332281,
umls-concept:C0332307,
umls-concept:C0333348,
umls-concept:C0441889,
umls-concept:C1801960,
umls-concept:C1882417,
umls-concept:C2745888
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pubmed:issue |
3
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pubmed:dateCreated |
2010-11-15
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pubmed:abstractText |
The Leucine7 to Proline7 (Leu7Pro) polymorphism of the signal peptide of neuropeptide Y (NPY) increases risk for vascular complications in diabetes. Diabetes is associated with low-grade inflammation, which has an important role in the development of atherosclerosis. Currently, we followed diabetes patients to investigate, if the Pro7 allele is associated with the inflammation related to atherosclerosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/C-Reactive Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Creatinine,
http://linkedlifedata.com/resource/pubmed/chemical/E-Selectin,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Neuropeptide Y,
http://linkedlifedata.com/resource/pubmed/chemical/Plasminogen Activator Inhibitor 1,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Sorting Signals,
http://linkedlifedata.com/resource/pubmed/chemical/SERPINE1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Amyloid P-Component
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1095-9319
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
433-9
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pubmed:meshHeading |
pubmed-meshheading:20691708-Aged,
pubmed-meshheading:20691708-Albuminuria,
pubmed-meshheading:20691708-Atherosclerosis,
pubmed-meshheading:20691708-Biological Markers,
pubmed-meshheading:20691708-C-Reactive Protein,
pubmed-meshheading:20691708-Creatinine,
pubmed-meshheading:20691708-Diabetes Mellitus, Type 2,
pubmed-meshheading:20691708-Diabetic Angiopathies,
pubmed-meshheading:20691708-E-Selectin,
pubmed-meshheading:20691708-Female,
pubmed-meshheading:20691708-Finland,
pubmed-meshheading:20691708-Follow-Up Studies,
pubmed-meshheading:20691708-Genetic Predisposition to Disease,
pubmed-meshheading:20691708-Humans,
pubmed-meshheading:20691708-Inflammation Mediators,
pubmed-meshheading:20691708-Insulin Resistance,
pubmed-meshheading:20691708-Linear Models,
pubmed-meshheading:20691708-Logistic Models,
pubmed-meshheading:20691708-Male,
pubmed-meshheading:20691708-Matched-Pair Analysis,
pubmed-meshheading:20691708-Middle Aged,
pubmed-meshheading:20691708-Neuropeptide Y,
pubmed-meshheading:20691708-Phenotype,
pubmed-meshheading:20691708-Plasminogen Activator Inhibitor 1,
pubmed-meshheading:20691708-Polymorphism, Genetic,
pubmed-meshheading:20691708-Protein Sorting Signals,
pubmed-meshheading:20691708-Risk Assessment,
pubmed-meshheading:20691708-Risk Factors,
pubmed-meshheading:20691708-Serum Amyloid P-Component,
pubmed-meshheading:20691708-Sex Factors,
pubmed-meshheading:20691708-Time Factors,
pubmed-meshheading:20691708-Up-Regulation,
pubmed-meshheading:20691708-Vasodilation
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pubmed:year |
2010
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pubmed:articleTitle |
The Leu7Pro polymorphism of the signal peptide of neuropeptide Y (NPY) gene is associated with increased levels of inflammatory markers preceding vascular complications in patients with type 2 diabetes.
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pubmed:affiliation |
Centre for Biotechnology, University of Turku, Tykistökatu 6, Turku, Finland. ulriikka.jaakkola@utu.fi
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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