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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2010-8-30
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pubmed:abstractText |
Interleukin-6 (IL-6) is a multifunctional cytokine that has been implicated in the modulation of growth and progression of prostate cancer. Decreased expression of the tyrosine phosphatase SHP-1, involved in regulation of cytokine and tyrosine kinase receptor signaling, has been shown to be associated with less favorable outcome among prostate cancer patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1097-0045
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2010 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1491-500
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pubmed:meshHeading |
pubmed-meshheading:20687222-Caspase 3,
pubmed-meshheading:20687222-Caspase 7,
pubmed-meshheading:20687222-Cell Division,
pubmed-meshheading:20687222-Cell Line, Tumor,
pubmed-meshheading:20687222-DNA Primers,
pubmed-meshheading:20687222-Disease Progression,
pubmed-meshheading:20687222-Down-Regulation,
pubmed-meshheading:20687222-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:20687222-Humans,
pubmed-meshheading:20687222-Immunohistochemistry,
pubmed-meshheading:20687222-Interleukin-6,
pubmed-meshheading:20687222-Kinetics,
pubmed-meshheading:20687222-Lymphatic Metastasis,
pubmed-meshheading:20687222-Male,
pubmed-meshheading:20687222-PTEN Phosphohydrolase,
pubmed-meshheading:20687222-Prostatic Neoplasms,
pubmed-meshheading:20687222-Protein Tyrosine Phosphatase, Non-Receptor Type 6,
pubmed-meshheading:20687222-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20687222-STAT3 Transcription Factor,
pubmed-meshheading:20687222-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Role of the protein tyrosine phosphatase SHP-1 in Interleukin-6 regulation of prostate cancer cells.
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pubmed:affiliation |
Department of Laboratory Medicin, Tumour Biology, Lund University, Malmö University Hospital, Malmö, Sweden. helena.tassidis@med.lu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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