Linked Life Data

20645055

Source:http://linkedlifedata.com/resource/pubmed/id/20645055

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-7-20
pubmed:abstractText
Highly differentiated normal human hepatocytes represent the gold standard cellular model for basic and applied research in liver physiopathology, pharmacology, toxicology, virology, and liver biotherapy. Nowadays, although livers from organ donors or medically required resections represent the current sources of hepatocytes, the possibility to generate hepatocytes from the differentiation of adult and embryonic stem cells represents a promising opportunity. The aim of this chapter is to describe our experience with the isolation from adult human liver and culture of non-parenchymal epithelial cells. Under appropriate conditions, these cells differentiate in vitro in hepatocyte-like cells and therefore appear to behave as liver progenitor cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1940-6029
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
640
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
247-60
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Isolation and culture of adult human liver progenitor cells: in vitro differentiation to hepatocyte-like cells.
pubmed:affiliation
INSERM U632, Hepatic Physiopathology, Montpellier, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't