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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
20
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pubmed:dateCreated |
2010-11-9
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pubmed:abstractText |
The intestine exhibits profound diurnal rhythms in function and morphology, in part due to changes in enterocyte proliferation. The regulatory mechanisms behind these rhythms remain largely unknown. We hypothesized that microRNAs are involved in mediating these rhythms, and studied the role of microRNAs specifically in modulating intestinal proliferation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1090-2422
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
316
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3512-21
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pubmed:dateRevised |
2011-10-5
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pubmed:meshHeading |
pubmed-meshheading:20633552-Animals,
pubmed-meshheading:20633552-Cell Enlargement,
pubmed-meshheading:20633552-Cell Line,
pubmed-meshheading:20633552-Cell Proliferation,
pubmed-meshheading:20633552-Circadian Rhythm,
pubmed-meshheading:20633552-Cyclin-Dependent Kinase 6,
pubmed-meshheading:20633552-Cyclins,
pubmed-meshheading:20633552-DNA,
pubmed-meshheading:20633552-Enterocytes,
pubmed-meshheading:20633552-G1 Phase,
pubmed-meshheading:20633552-Gene Expression,
pubmed-meshheading:20633552-Intestinal Mucosa,
pubmed-meshheading:20633552-Jejunum,
pubmed-meshheading:20633552-Male,
pubmed-meshheading:20633552-MicroRNAs,
pubmed-meshheading:20633552-Muscle, Smooth,
pubmed-meshheading:20633552-Photoperiod,
pubmed-meshheading:20633552-Rats,
pubmed-meshheading:20633552-Rats, Sprague-Dawley,
pubmed-meshheading:20633552-Transfection
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pubmed:year |
2010
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pubmed:articleTitle |
MicroRNA mir-16 is anti-proliferative in enterocytes and exhibits diurnal rhythmicity in intestinal crypts.
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pubmed:affiliation |
Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA. anita.balakrishnan@doctors.org.uk
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pubmed:publicationType |
Journal Article
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