Linked Life Data

20630247

Source:http://linkedlifedata.com/resource/pubmed/id/20630247

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-7-15
pubmed:abstractText
Studies have reported genetic variation in milk urea nitrogen (MUN) between cows, suggesting genetic differences in nitrogen efficiency between cows. In this paper, the results of a genome-wide scan to identify quantitative trait loci (QTL) that contribute to genetic variation in MUN and MUN yield are presented. Two to 3 morning milk samples were taken from 1,926 cows, resulting in 5,502 test-day records. Test-day records were corrected for systematic environmental effects using a repeatability animal model. Averages of corrected phenotypes of 849 cows, belonging to 7 sire families, were used in an across-family multimarker regression approach to detect QTL. Animals were successfully genotyped for 1,341 single nucleotide polymorphisms. The QTL analysis resulted in 4 chromosomal regions with suggestive QTL: Bos taurus autosomes (BTA) 1, 6, 21, and 23. On BTA 1, 2 suggestive QTL affecting MUN were detected at 60 and 140 cM. On BTA 6, 1 suggestive QTL affecting both MUN and MUN yield was detected at 103 cM. On BTA 21, 1 suggestive QTL affecting MUN yield was detected at 83 cM. On BTA 23, 1 suggestive QTL affecting MUN was detected at 54 cM. Quantitative trait loci for MUN and MUN yield were suggestive and each explained between 2 and 3% of the phenotypic variance.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1525-3198
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2010 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3310-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Genome-wide scan to detect quantitative trait loci for milk urea nitrogen in Dutch Holstein-Friesian cows.
pubmed:affiliation
Animal Breeding and Genomics Centre, Wageningen University, PO Box 338, 6700 AH Wageningen, the Netherlands. Aniek.Bouwman@wur.nl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't