Source:http://linkedlifedata.com/resource/pubmed/id/20614819
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-7-9
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pubmed:abstractText |
An investigation was made of the effects on endogenous antioxidant enzyme activities and H2O2-induced lipid peroxidation inhibition in human red blood cells of the crude MeOH extract and its EtOAc, n-BuOH, and H2O sub-extracts obtained from aerial parts of Geranium psilostemon Ledeb., as well as compounds isolated from the most active EtOAc extract. Gallic acid (1), methyl gallate (2), pusilagin (3), 1,3,6-tri-O-galloyl-beta-glucopyranoside (4), 1,2,3,4,6-penta-O-galloyl-beta-glucopyranoside (5), kaempferol (6), quercetin (7), kaempferol 7-O-alpha-rhamnopyranoside (8), and quercetin 7-O-alpha-rhamnopyranoside (9) were isolated from the aerial parts of the title plant, and their structures identified from spectroscopic (UV, 1D- and 2D- NMR) and spectrometric (TOF-MS) data. All extracts and isolated compounds inhibited H2O2-induced lipid peroxidation and also enhanced the activity of superoxide dismutase (SOD) and catalase (CAT).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1934-578X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
899-902
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pubmed:meshHeading |
pubmed-meshheading:20614819-Antioxidants,
pubmed-meshheading:20614819-Erythrocytes,
pubmed-meshheading:20614819-Geranium,
pubmed-meshheading:20614819-Humans,
pubmed-meshheading:20614819-Hydrogen Peroxide,
pubmed-meshheading:20614819-Lipid Peroxidation,
pubmed-meshheading:20614819-Plant Components, Aerial
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pubmed:year |
2010
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pubmed:articleTitle |
Antioxidant effects of secondary metabolites from Geranium psilostemon.
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pubmed:affiliation |
Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey. didems@hacettepe.edu.tr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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