Source:http://linkedlifedata.com/resource/pubmed/id/20613626
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2010-9-16
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pubmed:abstractText |
Sympathetic nerve hyperactivity has been associated with hypertension and heart failure and their cardiovascular complications. The ?2-adrenergic receptors have been proposed to play a prominent role in the control of sympathetic neural output, and their malfunction to constitute a potential central mechanism for sympathetic hyperactivity of essential hypertension. Reports on the relationship between variant alleles of ?2-adrenergic receptor subtypes and sympathetic drive or its effects, however, have not been consistent. Therefore, this study was planned to test the hypothesis that variant alleles of subtypes of ?2-adrenergic receptors are associated with raised muscle sympathetic nerve activity (MSNA) in man.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1473-5598
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2084-93
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pubmed:meshHeading |
pubmed-meshheading:20613626-Aging,
pubmed-meshheading:20613626-Alleles,
pubmed-meshheading:20613626-Blood Pressure,
pubmed-meshheading:20613626-Female,
pubmed-meshheading:20613626-Genotype,
pubmed-meshheading:20613626-Humans,
pubmed-meshheading:20613626-Hypertension,
pubmed-meshheading:20613626-Male,
pubmed-meshheading:20613626-Middle Aged,
pubmed-meshheading:20613626-Muscle, Skeletal,
pubmed-meshheading:20613626-Prospective Studies,
pubmed-meshheading:20613626-Receptors, Adrenergic, alpha-2,
pubmed-meshheading:20613626-Rest,
pubmed-meshheading:20613626-Sex Characteristics,
pubmed-meshheading:20613626-Sympathetic Nervous System
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pubmed:year |
2010
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pubmed:articleTitle |
Resting sympathetic nerve activity is related to age, sex and arterial pressure but not to ?2-adrenergic receptor subtype.
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pubmed:affiliation |
Division of Cardiovascular and Neuronal Remodelling, Leeds Institute of Genetics, Health and Therapeutics, Leeds, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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