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pubmed-article:20573471pubmed:abstractTextWe recently demonstrated in a murine model that nanoparticle-mediated delivery of pitavastatin into vascular endothelial cells effectively increased therapeutic neovascularization. For the development of a clinically applicable approach, further investigations are necessary to assess whether this novel system can induce the development of collateral arteries (arteriogenesis) in a chronic ischemia setting in larger animals.lld:pubmed
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pubmed-article:20573471pubmed:copyrightInfoCopyright (c) 2010 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.lld:pubmed
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pubmed-article:20573471pubmed:articleTitleNanoparticle-mediated endothelial cell-selective delivery of pitavastatin induces functional collateral arteries (therapeutic arteriogenesis) in a rabbit model of chronic hind limb ischemia.lld:pubmed
pubmed-article:20573471pubmed:affiliationDepartment of Cardiovascular Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.lld:pubmed
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