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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2010-9-27
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pubmed:abstractText |
To evaluate maximum tolerated dose and recommended dose (RD) for phase II studies of topotecan (TPT) combined with temozolomide (TMZ) (TOTEM) in children and adolescents with relapsed or refractory solid malignancies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1879-0852
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pubmed:author |
pubmed-author:AertsIsabelleI,
pubmed-author:ChastagnerPascalP,
pubmed-author:ChatelutEtienneE,
pubmed-author:CorradiniNadègeN,
pubmed-author:DiasNathalieN,
pubmed-author:DjafariLatifaL,
pubmed-author:FrappazDidierD,
pubmed-author:GentetJean-ClaudeJC,
pubmed-author:GeoergerBirgitB,
pubmed-author:Landman-ParkerJudithJ,
pubmed-author:Le DeleyMarie-CécileMC,
pubmed-author:LeblondPierreP,
pubmed-author:NdiayeAnnaA,
pubmed-author:PaciAngeloA,
pubmed-author:PasquetMarlèneM,
pubmed-author:RubieHervéH,
pubmed-author:SchmittAntoninA,
pubmed-author:VassalGillesG
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pubmed:copyrightInfo |
Copyright © 2010. Published by Elsevier Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2763-70
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pubmed:meshHeading |
pubmed-meshheading:20558056-Adolescent,
pubmed-meshheading:20558056-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20558056-Child,
pubmed-meshheading:20558056-Child, Preschool,
pubmed-meshheading:20558056-Dacarbazine,
pubmed-meshheading:20558056-Humans,
pubmed-meshheading:20558056-Infant,
pubmed-meshheading:20558056-Neoplasm Recurrence, Local,
pubmed-meshheading:20558056-Neoplasms,
pubmed-meshheading:20558056-Topotecan,
pubmed-meshheading:20558056-Treatment Outcome,
pubmed-meshheading:20558056-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Phase I study of topotecan in combination with temozolomide (TOTEM) in relapsed or refractory paediatric solid tumours.
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pubmed:affiliation |
Hôpital des Enfants, Toulouse, France. rubie.h@chu-toulouse.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase I
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