Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-5-3
pubmed:abstractText
Coronary artery disease remains the leading cause of early death and graft loss in renal transplant patients. The aim of this study was to identify clinical and echocardiographic parameters independently associated with the angiographically-determined severity of coronary atherosclerosis in long-term kidney transplant patients. Fifty-two kidney transplant recipients who underwent elective coronary angiography were reviewed retrospectively. Angiographic severity was evaluated using the modified Gensini index (MGI). The mean age at coronary angiography was 52.5+/-7.9 yr with a mean prior transplant duration of 118.1+/-58.8 months. Pearson correlation analysis demonstrated a positive correlation of MGI with transplant duration before coronary angiography and chronic allograft nephropathy, whereas an inverse correlation was demonstrated with ejection fraction and statin use. On subsequent multivariate linear regression analysis, transplant duration before coronary angiography, statin use, and ejection fraction were independently associated with the severity of coronary atherosclerosis in long-term kidney transplant patients. In summary, our study demonstrates that statin use, ejection fraction, and transplant duration before coronary angiography are independent parameters associated with the severity of coronary atherosclerosis in long-term kidney transplant patients. Further investigation is required to reduce the atherosclerotic burden in kidney transplant patients.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-10075613, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-10580071, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-10616849, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-10966499, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-11145943, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-11959338, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-12608551, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-12717218, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-12748349, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-12883196, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-14712439, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-15072511, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-15100371, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-1531347, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-15458484, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-16003232, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-16303007, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-16376782, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-16549162, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-19194569, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-2138525, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-3287917, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-6048074, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-6823874, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-6863543, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-7438407, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-8291117, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-8443896, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-8610370, http://linkedlifedata.com/resource/pubmed/commentcorrection/20436705-8808124
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1598-6357
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
706-11
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Correlates of the severity of coronary atherosclerosis in long-term kidney transplant patients.
pubmed:affiliation
Department of Internal Medicine, Wonkwang University College of Medicine Sanbon Hospital, Gunpo, Korea.
pubmed:publicationType
Journal Article, Clinical Trial