Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-4-16
pubmed:abstractText
The relationship between disorders in the cytoarchitectonics (microdysgenesis) and formation of epileptogenic zones was studied on clinical material. Results of surgical treatment of 29 patients with drug-resistant temporal epilepsy are presented. Intraoperative electrocorticography was carried out in all patients. Histological studies of the cortex from the zone of regular epileptic activity registration were carried out in 23 cases. A relationship between completeness of radical removal of the zone of regular epileptic activity and treatment results was detected. Histological studies of resected cortex revealed signs of microdysgenesis in all cases. The presence of similar changes in the zone of regular epileptic activity registration, resection of which is essential for attack control, suggests a pathogenetic relationship between microdysgenesis and generation of epileptic activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1573-8221
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
148
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
582-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Relationship between epileptogenesis and morphological changes in the cerebral cortex.
pubmed:affiliation
N. N. Burdenko Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia. ast@nsi.ru
pubmed:publicationType
Journal Article