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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-4-8
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pubmed:abstractText |
Familial partial lipodystrophy of the Dunnigan type (FPLD2) presents with a decrease of subcutaneous adipose tissue (SAT) in the limbs and trunk. As thyroid hormones (TH) play an important role in adipogenesis, we studied if SAT from subjects with FPLD2 have changes in the gene expression levels of monocarboxylate transporter 8 (MCT8), a TH transporter, and TH nuclear receptors and in iodothyronine deiodinases (DIOs) expression and activities that could affect TH bioavailability and action in white adipose tissue.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1557-9077
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
419-24
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pubmed:meshHeading |
pubmed-meshheading:20373986-Abdominal Fat,
pubmed-meshheading:20373986-Humans,
pubmed-meshheading:20373986-Iodide Peroxidase,
pubmed-meshheading:20373986-Lipodystrophy, Familial Partial,
pubmed-meshheading:20373986-Monocarboxylic Acid Transporters,
pubmed-meshheading:20373986-RNA, Messenger,
pubmed-meshheading:20373986-Subcutaneous Fat,
pubmed-meshheading:20373986-Thigh,
pubmed-meshheading:20373986-Thyroid Hormones
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|
pubmed:year |
2010
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|
pubmed:articleTitle |
Regional decrease of subcutaneous adipose tissue in patients with type 2 familial partial lipodystrophy is associated with changes in thyroid hormone metabolism.
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pubmed:affiliation |
Department of Medicine, University of Santiago de Compostela , Santiago de Compostela, Spain. joaquin.lado@ttuhsc.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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