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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-3-11
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pubmed:abstractText |
Abnormalities of brain white matter and oligodendroglia are replicated findings in schizophrenia research. The largely oligodendroglia-associated enzyme ADAM (A disintegrin and metalloprotease) 12 might be involved in the patho-physiology of schizophrenia, because the gene coding for human ADAM12 is located on chromosome 10q26.3, a gene locus which has been linked to schizophrenia, and some of its putative substrates are altered in schizophrenia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1814-1412
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
556-66
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pubmed:meshHeading |
pubmed-meshheading:20218926-ADAM Proteins,
pubmed-meshheading:20218926-Blotting, Western,
pubmed-meshheading:20218926-Chromosomes, Human, Pair 10,
pubmed-meshheading:20218926-Female,
pubmed-meshheading:20218926-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:20218926-Gyrus Cinguli,
pubmed-meshheading:20218926-Humans,
pubmed-meshheading:20218926-Male,
pubmed-meshheading:20218926-Membrane Proteins,
pubmed-meshheading:20218926-Middle Aged,
pubmed-meshheading:20218926-Oligodendroglia,
pubmed-meshheading:20218926-Prefrontal Cortex,
pubmed-meshheading:20218926-Reference Values,
pubmed-meshheading:20218926-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20218926-Schizophrenia,
pubmed-meshheading:20218926-Signal Transduction
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pubmed:year |
2010
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pubmed:articleTitle |
Reduced density of ADAM 12-immunoreactive oligodendrocytes in the anterior cingulate white matter of patients with schizophrenia.
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pubmed:affiliation |
Department of Psychiatry, University of Magdeburg, Leipziger Strasse 44, Magdeburg, Germany.
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pubmed:publicationType |
Journal Article
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