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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-4-12
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pubmed:abstractText |
A palmitoyl conjugate of an insect pentapeptide that occurs in diapausing insects causes a reversible cell-cycle arrest and suppresses mitochondrial respiration. This peptide compound also causes growth arrest in murine leukemic cell line expressing human gene Bcr/Abl and a farnesoyl peptide induces embryonic diapause in Bombyx mori. These results demonstrate that the insect peptide compounds can lead to the understanding of a common pathway in developmental arrest in animals and may provide a new peptidominetic analog in the development of biopharmaceuticals and pest management.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1873-5169
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pubmed:author |
pubmed-author:AnYingY,
pubmed-author:ImaiKunioK,
pubmed-author:ImanishiShigeoS,
pubmed-author:IshidaYojiY,
pubmed-author:ItoKikukatsuK,
pubmed-author:ItoShigekiS,
pubmed-author:MatsudaHirokazuH,
pubmed-author:MatsukawaKazushigeK,
pubmed-author:SatoYosinoriY,
pubmed-author:SuzukiKoichiK,
pubmed-author:UchiyamaYusukeY,
pubmed-author:YangPingP
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pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
827-33
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pubmed:meshHeading |
pubmed-meshheading:20206219-Animals,
pubmed-meshheading:20206219-Bombyx,
pubmed-meshheading:20206219-Cell Cycle,
pubmed-meshheading:20206219-Cell Line,
pubmed-meshheading:20206219-Cell Line, Tumor,
pubmed-meshheading:20206219-Cell Proliferation,
pubmed-meshheading:20206219-Cell Respiration,
pubmed-meshheading:20206219-Cells, Cultured,
pubmed-meshheading:20206219-Drosophila,
pubmed-meshheading:20206219-Female,
pubmed-meshheading:20206219-Fusion Proteins, bcr-abl,
pubmed-meshheading:20206219-Insect Proteins,
pubmed-meshheading:20206219-Mice,
pubmed-meshheading:20206219-Microscopy, Phase-Contrast,
pubmed-meshheading:20206219-Molecular Structure,
pubmed-meshheading:20206219-Moths,
pubmed-meshheading:20206219-Oligopeptides,
pubmed-meshheading:20206219-Rats
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pubmed:year |
2010
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pubmed:articleTitle |
A palmitoyl conjugate of insect pentapeptide Yamamarin arrests cell proliferation and respiration.
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pubmed:affiliation |
Department of Agro-Bioscience, Faculty of Agriculture, Iwate University, Morioka 020-8550, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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