|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
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|
pubmed:dateCreated |
2010-3-22
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|
pubmed:abstractText |
Cancer cells commonly show increased levels of glucose uptake and dependence. A potential strategy for the treatment of cancer may be the inhibition of basal glucose transport. We report here the synthesis of a small library of polyphenolic esters that inhibit basal glucose transport in H1299 lung and other cancer cells. These basal glucose transport inhibitors also inhibit cancer cell growth in H1299 cells, and these two activities appear to be correlated.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1464-3405
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|
pubmed:author |
|
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pubmed:copyrightInfo |
2010 Elsevier Ltd. All rights reserved.
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|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
20
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2191-4
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|
pubmed:dateRevised |
2011-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:20194024-Antineoplastic Agents,
pubmed-meshheading:20194024-Biological Transport,
pubmed-meshheading:20194024-Cell Death,
pubmed-meshheading:20194024-Cell Line, Tumor,
pubmed-meshheading:20194024-Cell Proliferation,
pubmed-meshheading:20194024-Flavonoids,
pubmed-meshheading:20194024-Glucose,
pubmed-meshheading:20194024-Humans,
pubmed-meshheading:20194024-Neoplasms,
pubmed-meshheading:20194024-Phenols,
pubmed-meshheading:20194024-Polyphenols
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|
pubmed:year |
2010
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|
pubmed:articleTitle |
Novel inhibitors of basal glucose transport as potential anticancer agents.
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|
pubmed:affiliation |
Department of Chemistry & Biochemistry, Ohio University, Athens, OH 45701, USA.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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