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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-6-14
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pubmed:abstractText |
Genetic susceptibility to systemic lupus erythematosus (SLE) is well established, with the HLA class II DRB1 and DQB1 loci demonstrating the strongest association. However, HLA may also influence SLE through novel biologic mechanisms in addition to genetic transmission of risk alleles. Evidence for increased maternal-offspring HLA class II compatibility in SLE and differences in maternal versus paternal transmission rates (parent-of-origin effects) and nontransmission rates (noninherited maternal antigen [NIMA] effects) in other autoimmune diseases have been reported. Thus, we investigated maternal-offspring HLA compatibility, parent-of-origin effects, and NIMA effects at DRB1 in SLE.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/5-M01-RR-00079,
http://linkedlifedata.com/resource/pubmed/grant/5R01-A1-063274-06,
http://linkedlifedata.com/resource/pubmed/grant/F31 AI075609-01A1,
http://linkedlifedata.com/resource/pubmed/grant/F31 AI075609-03,
http://linkedlifedata.com/resource/pubmed/grant/F31-AI-075609,
http://linkedlifedata.com/resource/pubmed/grant/K24 AR002175-01A1,
http://linkedlifedata.com/resource/pubmed/grant/K24-AR-02175,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR000079-32,
http://linkedlifedata.com/resource/pubmed/grant/N01 AR062277,
http://linkedlifedata.com/resource/pubmed/grant/N01-AR-62277,
http://linkedlifedata.com/resource/pubmed/grant/P01 AI083194-01,
http://linkedlifedata.com/resource/pubmed/grant/P01 AR049084-01,
http://linkedlifedata.com/resource/pubmed/grant/P01-AI-083194,
http://linkedlifedata.com/resource/pubmed/grant/P01-AR-049084,
http://linkedlifedata.com/resource/pubmed/grant/P20 RR020143-07,
http://linkedlifedata.com/resource/pubmed/grant/P20-RR-020143,
http://linkedlifedata.com/resource/pubmed/grant/R01 AI063274-06,
http://linkedlifedata.com/resource/pubmed/grant/R01 AR042460-06A1,
http://linkedlifedata.com/resource/pubmed/grant/R01 AR043274-14,
http://linkedlifedata.com/resource/pubmed/grant/R01 AR044804-05,
http://linkedlifedata.com/resource/pubmed/grant/R01 AR052300-01,
http://linkedlifedata.com/resource/pubmed/grant/R01-AR-043274-14,
http://linkedlifedata.com/resource/pubmed/grant/R01-AR-052300,
http://linkedlifedata.com/resource/pubmed/grant/R01-AR-22804,
http://linkedlifedata.com/resource/pubmed/grant/R01-AR-42460,
http://linkedlifedata.com/resource/pubmed/grant/R37 AI024717-18,
http://linkedlifedata.com/resource/pubmed/grant/R37-AI-24717
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1529-0131
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pubmed:author |
pubmed-author:BarcellosLisa FLF,
pubmed-author:BehrensTimothyT,
pubmed-author:BronsonPaola GPG,
pubmed-author:ClaasFrans HFH,
pubmed-author:CriswellLindsey ALA,
pubmed-author:GaffneyPatrick MPM,
pubmed-author:HarleyJohn BJB,
pubmed-author:KellyJennifer AJA,
pubmed-author:KomorowskiLeanne KLK,
pubmed-author:LaneJulie AJA,
pubmed-author:MaySuzanne LSL,
pubmed-author:MoserKathy LKL,
pubmed-author:NobleJanelleJ,
pubmed-author:RamsayPatricia PPP,
pubmed-author:SeldinMichael FMF,
pubmed-author:ThomsonGlenysG
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1712-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20191587-Alleles,
pubmed-meshheading:20191587-Female,
pubmed-meshheading:20191587-Gene Frequency,
pubmed-meshheading:20191587-Genetic Association Studies,
pubmed-meshheading:20191587-Genetic Predisposition to Disease,
pubmed-meshheading:20191587-Genotype,
pubmed-meshheading:20191587-HLA-DR Antigens,
pubmed-meshheading:20191587-HLA-DRB1 Chains,
pubmed-meshheading:20191587-Humans,
pubmed-meshheading:20191587-Lupus Erythematosus, Systemic,
pubmed-meshheading:20191587-Male,
pubmed-meshheading:20191587-Questionnaires
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pubmed:year |
2010
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pubmed:articleTitle |
Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus.
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pubmed:affiliation |
University of California, Berkeley, California 94720-7356, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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