Linked Life Data

20189955

Source:http://linkedlifedata.com/resource/pubmed/id/20189955

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-7-16
pubmed:abstractText
The Wnt/frizzled (Fzd) signal transduction cascade has been implicated in the proliferation, differentiation, and migration of many cell types, but the role of this pathway in cardiac fibroblast differentiation is not known. Our lab previously showed an up-regulation of Fzd-1 and -2 expression in myofibroblasts after myocardial infarction (MI), indicating a potential role for the Fzd receptor in fibroblast-myofibroblast differentiation. The present study was performed to further define the role of specific Wnt and Fzd proteins in the proliferation, migration, and differentiation of cardiac fibroblasts.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Actins, http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channel Agonists, http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channel Blockers, http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type I, http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type III, http://linkedlifedata.com/resource/pubmed/chemical/Fibronectins, http://linkedlifedata.com/resource/pubmed/chemical/Frizzled Receptors, http://linkedlifedata.com/resource/pubmed/chemical/Fzd1 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Fzd2 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled, http://linkedlifedata.com/resource/pubmed/chemical/TERT protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Telomerase, http://linkedlifedata.com/resource/pubmed/chemical/Wnt Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Wnt3 Protein, http://linkedlifedata.com/resource/pubmed/chemical/smooth muscle actin, rat
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1755-3245
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
514-23
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:20189955-Actins, pubmed-meshheading:20189955-Animals, pubmed-meshheading:20189955-Calcium Channel Agonists, pubmed-meshheading:20189955-Calcium Channel Blockers, pubmed-meshheading:20189955-Cell Differentiation, pubmed-meshheading:20189955-Cell Line, pubmed-meshheading:20189955-Cell Movement, pubmed-meshheading:20189955-Cell Proliferation, pubmed-meshheading:20189955-Collagen Type I, pubmed-meshheading:20189955-Collagen Type III, pubmed-meshheading:20189955-Fibroblasts, pubmed-meshheading:20189955-Fibronectins, pubmed-meshheading:20189955-Frizzled Receptors, pubmed-meshheading:20189955-Humans, pubmed-meshheading:20189955-Male, pubmed-meshheading:20189955-Myocardium, pubmed-meshheading:20189955-RNA Interference, pubmed-meshheading:20189955-Rats, pubmed-meshheading:20189955-Rats, Inbred Lew, pubmed-meshheading:20189955-Receptors, G-Protein-Coupled, pubmed-meshheading:20189955-Signal Transduction, pubmed-meshheading:20189955-Telomerase, pubmed-meshheading:20189955-Time Factors, pubmed-meshheading:20189955-Transfection, pubmed-meshheading:20189955-Wnt Proteins, pubmed-meshheading:20189955-Wnt3 Protein
pubmed:year
2010
pubmed:articleTitle
Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts.
pubmed:affiliation
Department of Pharmacology and Toxicology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, 50 Universiteitssingel, PO Box 616, 6200 MD Maastricht, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't