Source:http://linkedlifedata.com/resource/pubmed/id/20174969
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2010-5-12
|
| pubmed:abstractText |
To compare a quantitative assessment of contrast cardiovascular magnetic resonance (CMR) after ST-segment elevation myocardial infarction (STEMI) with visual analysis for predicting depressed ejection fraction (dEF) and major adverse cardiac events (MACE). 192 patients underwent CMR at 1 week and 6 months after STEMI. Three quantitative (initial slope, maximal signal intensity and contrast delay in first-pass imaging) and 2 visual perfusion indexes (hypoenhancement in first-pass and microvascular obstruction in late enhancement imaging (LE)) were determined. Quantification of infarct mass and visual assessment of the extent of transmural necrosis (ETN) were also performed. At 6 months, 69 patients displayed dEF. During follow-up (mean 655 days) 20 MACE (death, re-infarction, re-admission for heart failure) occurred. Perfusion quantification took longer (P < 0.001) and, in ROC curve analyses and the C-statistic, was not superior to visual perfusion analysis for predicting late EF or MACE (P = ns). Similarly, infarct size quantification was not superior to visual assessment of ETN (P = ns). In multivariate analyses, only visual assessment of ETN (per segment) predicted dEF (OR 1.30 95%CI [1.04-1.61], P = 0.02) and MACE (HR 1.38 95%CI [1.19-1.60], P < 0.001). Visual analysis of CMR after STEMI is not time consuming and predicts dEF and MACE comparable to quantification. ETN was the strongest parameter.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
1875-8312
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| pubmed:author |
pubmed-author:BodiVicenteV,
pubmed-author:ChaustreFabianF,
pubmed-author:ChorroFrancisco JFJ,
pubmed-author:HusserOliverO,
pubmed-author:LlacerAngelA,
pubmed-author:Lopez-LereuMaria PMP,
pubmed-author:MainarLuisL,
pubmed-author:MerlosPilarP,
pubmed-author:MonmeneuJose VJV,
pubmed-author:NunezJulioJ,
pubmed-author:RieggerGünter A JGA,
pubmed-author:RumizEvaE,
pubmed-author:SanchisJuanJ
|
| pubmed:issnType |
Electronic
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
559-69
|
| pubmed:dateRevised |
2011-11-1
|
| pubmed:meshHeading |
pubmed-meshheading:20174969-Chi-Square Distribution,
pubmed-meshheading:20174969-Comorbidity,
pubmed-meshheading:20174969-Contrast Media,
pubmed-meshheading:20174969-Female,
pubmed-meshheading:20174969-Heart Catheterization,
pubmed-meshheading:20174969-Humans,
pubmed-meshheading:20174969-Image Interpretation, Computer-Assisted,
pubmed-meshheading:20174969-Magnetic Resonance Imaging,
pubmed-meshheading:20174969-Male,
pubmed-meshheading:20174969-Middle Aged,
pubmed-meshheading:20174969-Myocardial Infarction,
pubmed-meshheading:20174969-Myocardial Stunning,
pubmed-meshheading:20174969-Necrosis,
pubmed-meshheading:20174969-Predictive Value of Tests,
pubmed-meshheading:20174969-Proportional Hazards Models,
pubmed-meshheading:20174969-Prospective Studies,
pubmed-meshheading:20174969-ROC Curve
|
| pubmed:year |
2010
|
| pubmed:articleTitle |
Head to head comparison of quantitative versus visual analysis of contrast CMR in the setting of myocardial stunning after STEMI: implications on late systolic function and patient outcome.
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| pubmed:affiliation |
Department of Cardiology, Hospital Clinico Universitario, INCLIVA, Universidad de Valencia, Blasco Ibanez 17, 46010, Valencia, Spain.
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|