20167972

Source:http://linkedlifedata.com/resource/pubmed/id/20167972

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017398, umls-concept:C0225892, umls-concept:C0233820, umls-concept:C0265857, umls-concept:C0349788, umls-concept:C0878544, umls-concept:C1305586, umls-concept:C1707455, umls-concept:C2347963
pubmed:dateCreated	2010-2-19
pubmed:abstractText	Among the right ventricular conditions, Uhl's anomaly, arrhythmogenic right ventricular dysplasia / cardiomyopathy (ARVD/C) and right ventricular outflow tract ventricular tachycardia (RVOT VT) are disorders that exhibit pathogenic changes involving the right ventricular (RV) myocardium, and are expected to be severe or milder forms of the same condition. The review focuses on the aspect whether the three RV disorders are a spectrum of the same disease. ARVD/C is the only condition among these to be genetically well characterized. Also, variations in the clinical expression of ARVD/C due to the genetic heterogeneity are examined. Based on clinical manifestations, age at onset, gender ratio and the possible molecular mechanisms implicated, Uhl's anomaly, ARVD/C and RVOT VT may be considered as separate entities. Further, to differentiate between the three RV disorders, the molecular studies on ARVD/C might be helpful. An attempt was made to differentiate between the eleven different types of ARVD/Cs based on clinical symptoms presented including the progression of the disease to the left ventricle, ventricular arrhythmias and clinical characteristics like ECG, SAECG, ECHO and histopathological studies.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0374701
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	0971-5916
pubmed:author	pubmed-author:DokuparthiMaithili V NMV, pubmed-author:NallariPratibhaP, pubmed-author:NarasimhanCalamburC, pubmed-author:PamuruPranathi RPR, pubmed-author:RemersuSushantS
pubmed:issnType	Print
pubmed:volume	131
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	35-45
pubmed:meshHeading	pubmed-meshheading:20167972-Arrhythmogenic Right Ventricular Dysplasia, pubmed-meshheading:20167972-Gene Expression Profiling, pubmed-meshheading:20167972-Heart Defects, Congenital, pubmed-meshheading:20167972-Humans, pubmed-meshheading:20167972-Tachycardia, Ventricular
pubmed:year	2010
pubmed:articleTitle	Comparison of Uhl's anomaly, right ventricular outflow tract ventricular tachycardia (RVOT VT) & arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) with an insight into genetics of ARVD/C.
pubmed:affiliation	Department of Genetics, Osmania University, and Cardiology Care Hospital, The Institute of Medical Sciences, Hyderabad, India.
pubmed:publicationType	Journal Article, Comparative Study, Review