pubmed-article:2014713 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2014713 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
pubmed-article:2014713 | lifeskim:mentions | umls-concept:C0013303 | lld:lifeskim |
pubmed-article:2014713 | lifeskim:mentions | umls-concept:C0521457 | lld:lifeskim |
pubmed-article:2014713 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:2014713 | lifeskim:mentions | umls-concept:C0597196 | lld:lifeskim |
pubmed-article:2014713 | lifeskim:mentions | umls-concept:C1829747 | lld:lifeskim |
pubmed-article:2014713 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:2014713 | pubmed:dateCreated | 1991-5-10 | lld:pubmed |
pubmed-article:2014713 | pubmed:abstractText | The tendency to form a beta-turn in alpha-gliadin was estimated using the B-cell determinant prediction program based on the Chou and Fasman probability of beta-turn formation. Six sequences possessing a high probability of beta-turn formation were found. A statistically high agreement was found between these six sequences and three areas in alpha-gliadin with the occurrence of Pro-Ser-Gln-Gln sequence which has recently been considered responsible for toxicity in coeliac disease. By means of solid-phase synthesis seven peptides were obtained covering the above-mentioned regions. Their toxicity was tested using the fetal chick duodenum. The results support the suggestion that peptides containing the sequences Pro-Ser-Gln-Gln and Gln-Gln-Gln-Pro may be involved in the pathogenesis of coeliac disease. | lld:pubmed |
pubmed-article:2014713 | pubmed:language | eng | lld:pubmed |
pubmed-article:2014713 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2014713 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2014713 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2014713 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2014713 | pubmed:month | Feb | lld:pubmed |
pubmed-article:2014713 | pubmed:issn | 0044-3026 | lld:pubmed |
pubmed-article:2014713 | pubmed:author | pubmed-author:FricPP | lld:pubmed |
pubmed-article:2014713 | pubmed:author | pubmed-author:KrchnákVV | lld:pubmed |
pubmed-article:2014713 | pubmed:author | pubmed-author:MothesTT | lld:pubmed |
pubmed-article:2014713 | pubmed:author | pubmed-author:KocnaPP | lld:pubmed |
pubmed-article:2014713 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2014713 | pubmed:volume | 192 | lld:pubmed |
pubmed-article:2014713 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2014713 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2014713 | pubmed:pagination | 116-9 | lld:pubmed |
pubmed-article:2014713 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
pubmed-article:2014713 | pubmed:meshHeading | pubmed-meshheading:2014713-... | lld:pubmed |
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pubmed-article:2014713 | pubmed:meshHeading | pubmed-meshheading:2014713-... | lld:pubmed |
pubmed-article:2014713 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:2014713 | pubmed:articleTitle | Relationship between gliadin peptide structure and their effect on the fetal chick duodenum. | lld:pubmed |
pubmed-article:2014713 | pubmed:affiliation | Laboratory of Gastroenterology, Faculty of General Medicine, Charles University, Prague, Czechoslovakia. | lld:pubmed |
pubmed-article:2014713 | pubmed:publicationType | Journal Article | lld:pubmed |