Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7-8
pubmed:dateCreated
2010-4-12
pubmed:abstractText
Vitamin B(12), or B(12), is an essential nutrient for humans, and its deficiency is a public health problem, especially in elderly population. Around 30% of circulating total B(12) levels are attached to transcobalamin II (TCN2), being referred as holotranscobalamin (holo-TC), and representing the biologically active fraction. After cellular uptake, B(12) participates in the homocysteine (Hcy) metabolism. The potential influence of the described TCN2 776CNG polymorphism upon B(12) intracellular delivery is a current target of research and we aimed to investigate its biochemical significance upon a healthy adult population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1873-2933
pubmed:author
pubmed:copyrightInfo
2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
645-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The TCN2 776CNG polymorphism correlates with vitamin B(12) cellular delivery in healthy adult populations.
pubmed:affiliation
Research Institute for Medicines and Pharmaceutical Sciences, University of Lisbon, Portugal. rcastro@ff.ul.pt
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't