Source:http://linkedlifedata.com/resource/pubmed/id/20144600
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7-8
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pubmed:dateCreated |
2010-4-12
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pubmed:abstractText |
Vitamin B(12), or B(12), is an essential nutrient for humans, and its deficiency is a public health problem, especially in elderly population. Around 30% of circulating total B(12) levels are attached to transcobalamin II (TCN2), being referred as holotranscobalamin (holo-TC), and representing the biologically active fraction. After cellular uptake, B(12) participates in the homocysteine (Hcy) metabolism. The potential influence of the described TCN2 776CNG polymorphism upon B(12) intracellular delivery is a current target of research and we aimed to investigate its biochemical significance upon a healthy adult population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1873-2933
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pubmed:author | |
pubmed:copyrightInfo |
2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
645-9
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pubmed:meshHeading |
pubmed-meshheading:20144600-Adult,
pubmed-meshheading:20144600-Female,
pubmed-meshheading:20144600-Folic Acid,
pubmed-meshheading:20144600-Genotype,
pubmed-meshheading:20144600-Homocysteine,
pubmed-meshheading:20144600-Humans,
pubmed-meshheading:20144600-Male,
pubmed-meshheading:20144600-Middle Aged,
pubmed-meshheading:20144600-Phenotype,
pubmed-meshheading:20144600-Polymorphism, Genetic,
pubmed-meshheading:20144600-Transcobalamins,
pubmed-meshheading:20144600-Vitamin B 12
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pubmed:year |
2010
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pubmed:articleTitle |
The TCN2 776CNG polymorphism correlates with vitamin B(12) cellular delivery in healthy adult populations.
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pubmed:affiliation |
Research Institute for Medicines and Pharmaceutical Sciences, University of Lisbon, Portugal. rcastro@ff.ul.pt
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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