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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-1-27
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pubmed:abstractText |
Beta-thalassemia major is a unique disease characterized by early diastolic dysfunction, related exclusively to iron myocardial deposition. N-terminal-proBNP(amino-terminal) (NT-proBNP) and B-type natriuretic peptide (BNP) are sensitive biomarkers for the detection of asymptomatic left ventricular (LV) dysfunction, and they have important diagnostic and prognostic implications. Using beta-thalassemia as a model disease with isolated diastolic dysfunction, we sought to investigate the predictive value of NT-proBNP and BNP levels in comparison with the conventional and new Doppler echocardiography indexes in detecting this disorder.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1097-6744
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
159
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
68-74
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pubmed:meshHeading |
pubmed-meshheading:20102869-Adolescent,
pubmed-meshheading:20102869-Analysis of Variance,
pubmed-meshheading:20102869-Biological Markers,
pubmed-meshheading:20102869-Case-Control Studies,
pubmed-meshheading:20102869-Echocardiography, Doppler,
pubmed-meshheading:20102869-Female,
pubmed-meshheading:20102869-Heart Failure, Diastolic,
pubmed-meshheading:20102869-Humans,
pubmed-meshheading:20102869-Linear Models,
pubmed-meshheading:20102869-Male,
pubmed-meshheading:20102869-Natriuretic Peptide, Brain,
pubmed-meshheading:20102869-Observer Variation,
pubmed-meshheading:20102869-Peptide Fragments,
pubmed-meshheading:20102869-Predictive Value of Tests,
pubmed-meshheading:20102869-Probability,
pubmed-meshheading:20102869-Prognosis,
pubmed-meshheading:20102869-ROC Curve,
pubmed-meshheading:20102869-Reference Values,
pubmed-meshheading:20102869-Risk Assessment,
pubmed-meshheading:20102869-Severity of Illness Index,
pubmed-meshheading:20102869-Statistics, Nonparametric,
pubmed-meshheading:20102869-Ventricular Dysfunction, Left,
pubmed-meshheading:20102869-Young Adult,
pubmed-meshheading:20102869-beta-Thalassemia
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pubmed:year |
2010
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pubmed:articleTitle |
Predictive value of B-type natriuretic peptides in detecting latent left ventricular diastolic dysfunction in beta-thalassemia major.
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pubmed:affiliation |
2nd University Department of Cardiology, Attikon General Hospital, Athens, Greece.
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pubmed:publicationType |
Journal Article,
Comparative Study
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