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pubmed-article:20096470pubmed:abstractText?1-adrenoceptors (?1-ARs) are the predominant receptors in regulating heart functions. ?1-ARs contain 7-transmembrane domains (7TM), 3 extracellular loops and 3 intracellular loops. Among these loops, the second extracellular loop of ?1-AR (?1-AR-ECII) plays an important role in the pathogenesis of heart failure.lld:pubmed
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pubmed-article:20096470pubmed:copyrightInfoCopyright © 2009 Elsevier Ireland Ltd. All rights reserved.lld:pubmed
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pubmed-article:20096470pubmed:articleTitleLong-term active immunization with a synthetic peptide corresponding to the second extracellular loop of ?1-adrenoceptor induces both morphological and functional cardiomyopathic changes in rats.lld:pubmed
pubmed-article:20096470pubmed:affiliationDepartment of Physiology, Shanxi Medical University, Taiyuan 030001, PR China.lld:pubmed
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pubmed-article:20096470pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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