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pubmed-article:20051879pubmed:abstractTextTorcetrapib, a prototype cholesteryl ester transfer protein (CETP) inhibitor with potential for decreasing atherosclerotic disease, increased cardiovascular events in clinical trials. The identified hypertensive and aldosterone-elevating actions of torcetrapib may not fully account for this elevated cardiovascular risk. Therefore, we evaluated the effects of torcetrapib on endothelial mediated vasodilation in vivo.lld:pubmed
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pubmed-article:20051879pubmed:articleTitleTorcetrapib produces endothelial dysfunction independent of cholesteryl ester transfer protein inhibition.lld:pubmed
pubmed-article:20051879pubmed:affiliationJohnson & Johnson Pharmaceutical Research and Development, Welsh & McKean Roads, Spring House, PA 19477-0776, USA. mconnell@its.jnj.comlld:pubmed
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