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pubmed-article:20041176pubmed:abstractTextOsmotic Response Element-Binding Protein (OREBP), also known as TonEBP or NFAT5, is a unique transcription factor. It is hitherto the only known mammalian transcription factor that regulates hypertonic stress-induced gene transcription. In addition, unlike other monomeric members of the NFAT family, OREBP exists as a homodimer and it is the only transcription factor known to bind naked DNA targets by complete encirclement in vitro. Nevertheless, how OREBP interacts with target DNA, also known as ORE/TonE, and how it elicits gene transcription in vivo, remains unknown.lld:pubmed
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pubmed-article:20041176pubmed:authorpubmed-author:ChungSookja...lld:pubmed
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pubmed-article:20041176pubmed:authorpubmed-author:TongEdith H...lld:pubmed
pubmed-article:20041176pubmed:authorpubmed-author:GuoJin-JunJJlld:pubmed
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pubmed-article:20041176pubmed:dateRevised2010-9-28lld:pubmed
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