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pubmed-article:2004090pubmed:abstractTextA table comparing the number of syndromes with orofacial clefting for the years 1971, 1978, and 1990 is presented and discussed. Over 300 such disorders are known today. A second table is presented showing the frequency of associated anomalies with orofacial clefting. The wide range of frequencies found in various studies probably reflects the type of ascertainment. Undoubtedly, the process of syndrome delineation will further increase the number of disorders with orofacial clefting in the future.lld:pubmed
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pubmed-article:2004090pubmed:dateRevised2005-11-16lld:pubmed
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pubmed-article:2004090pubmed:articleTitleSyndrome delineation involving orofacial clefting.lld:pubmed
pubmed-article:2004090pubmed:affiliationDepartment of Oral Biology, Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada.lld:pubmed
pubmed-article:2004090pubmed:publicationTypeJournal Articlelld:pubmed
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