Linked Life Data

20024904

Source:http://linkedlifedata.com/resource/pubmed/id/20024904

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-6-21
pubmed:abstractText
To date, a number of high-profile studies have yielded over 50 inflammatory bowel disease (IBD) disease genes/loci. The polymorphisms rs9858542 (BSN) and rs3197999 (MST1), on 3p21 locus, have been found associated with susceptibility to IBD. We aimed to replicate these associations in adult and early-onset cohorts of IBD Italian patients, by analyzing also potential gene-gene interactions with variants in NOD2/CARD15, IL23R, ATG16L1, and IRGM genes, and investigating genotype-phenotype correlation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1536-4844
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1108-17
pubmed:meshHeading
pubmed-meshheading:20024904-Adolescent, pubmed-meshheading:20024904-Adult, pubmed-meshheading:20024904-Aged, pubmed-meshheading:20024904-Aged, 80 and over, pubmed-meshheading:20024904-Carrier Proteins, pubmed-meshheading:20024904-Child, pubmed-meshheading:20024904-Child, Preschool, pubmed-meshheading:20024904-Chromosomes, Human, Pair 3, pubmed-meshheading:20024904-Colitis, Ulcerative, pubmed-meshheading:20024904-Crohn Disease, pubmed-meshheading:20024904-Female, pubmed-meshheading:20024904-GTP-Binding Proteins, pubmed-meshheading:20024904-Genetic Association Studies, pubmed-meshheading:20024904-Genetic Predisposition to Disease, pubmed-meshheading:20024904-Genotype, pubmed-meshheading:20024904-Haplotypes, pubmed-meshheading:20024904-Humans, pubmed-meshheading:20024904-Infant, pubmed-meshheading:20024904-Male, pubmed-meshheading:20024904-Middle Aged, pubmed-meshheading:20024904-Nod2 Signaling Adaptor Protein, pubmed-meshheading:20024904-Phenotype, pubmed-meshheading:20024904-Polymorphism, Single Nucleotide, pubmed-meshheading:20024904-Receptors, Interleukin, pubmed-meshheading:20024904-Young Adult
pubmed:year
2010
pubmed:articleTitle
Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease.
pubmed:affiliation
Division of Gastroenterology & Endoscopy, Casa Sollievo della Sofferenza Hospital, IRCCS, San Giovanni Rotondo, Italy.
pubmed:publicationType
Journal Article