20002098

Source:http://linkedlifedata.com/resource/pubmed/id/20002098

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011923, umls-concept:C0032743, umls-concept:C0032961, umls-concept:C0033147, umls-concept:C0040300, umls-concept:C1753353
pubmed:issue	2
pubmed:dateCreated	2010-2-9
pubmed:abstractText	Changes in tissue P-glycoprotein (P-gp) activity during pregnancy could affect the pharmacokinetics and thus the efficacy and toxicity of many drugs. Therefore, using positron emission tomography (PET) imaging, we tested whether gestational age affects tissue P-gp activity in the pregnant non-human primate, Macaca nemestrina.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/GM032165, http://linkedlifedata.com/resource/pubmed/grant/P50HD044404, http://linkedlifedata.com/resource/pubmed/grant/RR00166, http://linkedlifedata.com/resource/pubmed/grant/U10HD047892
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-10562306, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-12183111, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-12902425, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-12960202, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-14534356, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-14617681, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-14642487, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-14833874, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-15695792, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-15708129, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-15917342, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-15961534, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-15961982, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-16084847, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-16143395, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-16293715, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-16364611, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-16415090, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-16537797, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-16563694, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-18057117, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-18093255, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-18194223, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-18347570, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-19026953, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-19050320, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-19403878, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-19478134, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-8096515, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-811413, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-9080480, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-9717696, http://linkedlifedata.com/resource/pubmed/commentcorrection/20002098-9762726
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7502536
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cyclosporine, http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein, http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals, http://linkedlifedata.com/resource/pubmed/chemical/Verapamil
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1476-5381
pubmed:author	pubmed-author:ChungF SFS, pubmed-author:DUNNK RKR, pubmed-author:HsiaoPP, pubmed-author:KaddoumiAA, pubmed-author:LinkJ MJM, pubmed-author:MankoffD ADA, pubmed-author:MuziMM, pubmed-author:O'SullivanFF, pubmed-author:UnadkatJ DJD
pubmed:issnType	Electronic
pubmed:day	1
pubmed:volume	159
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	394-404
pubmed:dateRevised	2011-7-19
pubmed:meshHeading	pubmed-meshheading:20002098-Animals, pubmed-meshheading:20002098-Blood-Brain Barrier, pubmed-meshheading:20002098-Cyclosporine, pubmed-meshheading:20002098-Female, pubmed-meshheading:20002098-Gestational Age, pubmed-meshheading:20002098-Macaca nemestrina, pubmed-meshheading:20002098-Maternal-Fetal Exchange, pubmed-meshheading:20002098-Organ Specificity, pubmed-meshheading:20002098-P-Glycoprotein, pubmed-meshheading:20002098-Placenta, pubmed-meshheading:20002098-Positron-Emission Tomography, pubmed-meshheading:20002098-Pregnancy, pubmed-meshheading:20002098-Pregnancy, Animal, pubmed-meshheading:20002098-Radiopharmaceuticals, pubmed-meshheading:20002098-Verapamil
pubmed:year	2010
pubmed:articleTitle	Positron emission tomography imaging of tissue P-glycoprotein activity during pregnancy in the non-human primate.
pubmed:affiliation	Department of Pharmaceutics, University of Washington, Seattle, Washington 98195, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural