Linked Life Data

1997083

Source:http://linkedlifedata.com/resource/pubmed/id/1997083

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-3-29
pubmed:abstractText
In a double blind trial 72 patients having elective aortic surgery were randomized to receive either 40 ml of 0.25% bupivacaine or 40 ml of saline through one or two indwelling wound irrigation catheters every four hours over a total of 48 hours. In transverse incisions the two catheters were randomly placed either subcutaneously or in the rectus sheath; in vertical incisions one catheter was placed subcutaneously. Analgesia was assessed by visual analogue score on Postoperative Days 1 and 2 and the number of doses of intramuscular morphine given during the instillation period. Pulmonary function was monitored by forced expiratory volume and peak flow on Postoperative Days 1 to 5; arterial blood gases were monitored preoperatively and Postoperative Day 2. In all parameters evaluated there was no statistically significant difference between the saline (n = 33) or the bupivacaine (n = 37) groups. Site of the catheter in the transverse groups made no difference. Comparing vertical (n = 21) and transverse (n = 49) incisions, the mean visual analogue scores on the first postoperative day were 40 and 29, respectively (p less than 0.05). Wound instillation with bupivacaine neither improves pulmonary function nor reduces morphine requirements when compared to saline. Transverse incisions may be less painful than vertical ones.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0890-5096
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
80-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Wound instillation for postoperative pain relief: a comparison between bupivacaine and saline in patients undergoing aortic surgery.
pubmed:affiliation
Department of Vascular Surgery, Royal Liverpool Hospital, England.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial