Linked Life Data

19963627

Source:http://linkedlifedata.com/resource/pubmed/id/19963627

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-12-7
pubmed:abstractText
A wearable cardiopulmonary monitoring system, a LifeShirt, was used to acquire continuous electrocardiograms (ECGs) from ambulatory swine. The animals received intracoronary injections of autologous mesenchymal stem cells, and the LifeShirt was used for long-duration ECG monitoring in pre-defined periods post cell infusion. The system used here was developed for measurements from non-human primates and canines; however, we demonstrated that it could be used to non-invasively measure ECGs from swine without creating undue stress or restricting movement. A MATLAB-based analysis algorithm was developed to automatically detect premature ventricular contractions (PVCs) that arose 8-10 hours after cell delivery with spontaneous resolution 2-3 days post-infusion. Template based cross-correlation was used to detect the PVCs and identify regions of consecutive ventricular rhythm. The final algorithm was highly specific and sensitive when tested on records from the MIT-BIH arrhythmia database. The algorithm was subsequently used to automatically identify and quantify PVCs from over 200 hours of ECG data obtained from nine ambulatory swine.
pubmed:grant
http://linkedlifedata.com/resource/pubmed/grant/P01 HL078931-01A10003, http://linkedlifedata.com/resource/pubmed/grant/P01 HL078931-020003, http://linkedlifedata.com/resource/pubmed/grant/P01 HL078931-030003, http://linkedlifedata.com/resource/pubmed/grant/P01 HL078931-040003, http://linkedlifedata.com/resource/pubmed/grant/P01 HL078931-050003, http://linkedlifedata.com/resource/pubmed/grant/R01 HL071140-01, http://linkedlifedata.com/resource/pubmed/grant/R01 HL071140-02, http://linkedlifedata.com/resource/pubmed/grant/R01 HL071140-03, http://linkedlifedata.com/resource/pubmed/grant/R01 HL071140-04, http://linkedlifedata.com/resource/pubmed/grant/R01 HL071140-05A1, http://linkedlifedata.com/resource/pubmed/grant/R01 HL078932-01, http://linkedlifedata.com/resource/pubmed/grant/R01 HL078932-02, http://linkedlifedata.com/resource/pubmed/grant/R01 HL078932-03, http://linkedlifedata.com/resource/pubmed/grant/R01 HL078932-04, http://linkedlifedata.com/resource/pubmed/grant/T32 HL079995-03
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
2009
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4820-3
pubmed:dateRevised
2011-5-9
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
LifeShirt acquisition system to monitor ECG from ambulatory swine and the implementation of an arrhythmia detection algorithm.
pubmed:affiliation
Indiana Center for Vascular Biology and Medicine (ICVBM), Indiana University School of Medicine, Indianapolis, IN 46202, USA. akyle@iupui.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural