pubmed-article:1988159 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0205252 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0229951 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0814999 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0021755 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0026249 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0033414 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0178555 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0150312 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:1988159 | lifeskim:mentions | umls-concept:C1514485 | lld:lifeskim |
pubmed-article:1988159 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:1988159 | pubmed:dateCreated | 1991-2-22 | lld:pubmed |
pubmed-article:1988159 | pubmed:abstractText | Three thymic epithelial cell lines (TEC1C5, TEC1-4, and TEC2-3) were established from the thymus of newborn C57BL/6 mice. TEC1C5 was revealed to be an interleukin (IL)-1 producing cell line. TEC1-4 produced a cofactor to promote proliferation of double negative (CD4-8-) thymic lymphocytes by the presence of IL-1. Production of the same cofactor was also seen in TEC2-3, but only when it was cultured by the presence of indomethacin. The chemical analysis of the TEC1-4 culture supernatant by ion-exchange column and sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that the factor was approximately 35 kDa in molecular weight. The present study revealed that a factor produced by TEC1-4 acted as a cofactor to promote the proliferation of immature T cells stimulated by IL-1 and various mitogens and was considered to be a new one in terms of molecular weight. | lld:pubmed |
pubmed-article:1988159 | pubmed:language | eng | lld:pubmed |
pubmed-article:1988159 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1988159 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1988159 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1988159 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1988159 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1988159 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1988159 | pubmed:month | Feb | lld:pubmed |
pubmed-article:1988159 | pubmed:issn | 0008-8749 | lld:pubmed |
pubmed-article:1988159 | pubmed:author | pubmed-author:KasaiMM | lld:pubmed |
pubmed-article:1988159 | pubmed:author | pubmed-author:HirokawaKK | lld:pubmed |
pubmed-article:1988159 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1988159 | pubmed:volume | 132 | lld:pubmed |
pubmed-article:1988159 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1988159 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1988159 | pubmed:pagination | 377-90 | lld:pubmed |
pubmed-article:1988159 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
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pubmed-article:1988159 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:1988159 | pubmed:articleTitle | A novel cofactor produced by a thymic epithelial cell line: promotion of proliferation of immature thymic lymphocytes by the presence of interleukin-1 and various mitogens. | lld:pubmed |
pubmed-article:1988159 | pubmed:affiliation | Department of Pathology, Tokyo Metropolitan Institute of Gerontology, Japan. | lld:pubmed |
pubmed-article:1988159 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1988159 | lld:pubmed |