19878866

Source:http://linkedlifedata.com/resource/pubmed/id/19878866

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C2239176
pubmed:issue	5
pubmed:dateCreated	2009-11-2
pubmed:abstractText	Mst1 and Mst2 are key components of the Hippo tumor suppressor pathway. In this issue, Zhou et al. (2009) reported that Mst1/2 ablation leads to hepatocellular carcinomas. Unexpectedly, Mst1/2 may activate another kinase besides Lats1 and Lats2 to phosphorylate YAP, and the role of Mst1/2 in YAP regulation is cell type dependent.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/19878866-19878874
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101130617
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Mst2 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Stk4 protein, mouse
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1878-3686
pubmed:author	pubmed-author:GuanKun-LiangKL, pubmed-author:LeiQunyingQ, pubmed-author:ZhaoBinB
pubmed:issnType	Electronic
pubmed:day	6
pubmed:volume	16
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	363-4
pubmed:meshHeading	pubmed-meshheading:19878866-Animals, pubmed-meshheading:19878866-Liver Neoplasms, Experimental, pubmed-meshheading:19878866-Mice, pubmed-meshheading:19878866-Mice, Knockout, pubmed-meshheading:19878866-Protein-Serine-Threonine Kinases
pubmed:year	2009
pubmed:articleTitle	Mst out and HCC in.
pubmed:affiliation	Department of Pharmacology and Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093-0815, USA.
pubmed:publicationType	Journal Article, Comment