Source:http://linkedlifedata.com/resource/pubmed/id/19843034
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
2009-10-21
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| pubmed:abstractText |
The aim of our study was to investigate the ability of Strain-Encoded magnetic resonance imaging (MRI) to detect cardiac allograft vasculopathy (CAV) in heart transplantation (HTx)-recipients. In consecutive subjects (n = 69), who underwent cardiac catheterization, MRI was performed for quantification of myocardial strain and perfusion reserve. Based on angiographic findings subjects were classified: group A including patients with normal vessels; group B, patients with stenosis <50%; and group C, patients with severe CAV (stenosis >or= 50%). Significant correlations were observed between myocardial perfusion reserve with peak systolic strain (r =-0.53, p < 0.001) and with mean diastolic strain rate (r = 0.82, p < 0.001). Peak systolic strain and strain rate were significantly reduced only in group C, while mean diastolic strain rate and myocardial perfusion reserve were already reduced in group B and A. Myocardial perfusion reserve and mean diastolic strain rate had higher accuracy for the detection of CAV (AUC = 0.95, 95% CI = 0.87-0.99 and AUC = 0.93, 95% CI = 0.84-0.98, respectively) and followed peak systolic strain and strain rate (AUC = 0.80, 95% CI = 0.69-0.89 and AUC = 0.78, 95% CI = 0.67-0.87, respectively). Besides the quantification of myocardial perfusion, the estimation of the diastolic strain rate is a useful parameter for CAV assessment. In combination with the clinical evaluation, these parameters may be effective tools for the routine surveillance of HTx-recipients.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
1600-6143
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
9
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
2587-96
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| pubmed:meshHeading |
pubmed-meshheading:19843034-Adult,
pubmed-meshheading:19843034-Aged,
pubmed-meshheading:19843034-Chronic Disease,
pubmed-meshheading:19843034-Coronary Angiography,
pubmed-meshheading:19843034-Coronary Artery Disease,
pubmed-meshheading:19843034-Coronary Circulation,
pubmed-meshheading:19843034-Diastole,
pubmed-meshheading:19843034-Exercise Test,
pubmed-meshheading:19843034-Female,
pubmed-meshheading:19843034-Graft Survival,
pubmed-meshheading:19843034-Heart Transplantation,
pubmed-meshheading:19843034-Humans,
pubmed-meshheading:19843034-Magnetic Resonance Imaging,
pubmed-meshheading:19843034-Male,
pubmed-meshheading:19843034-Middle Aged,
pubmed-meshheading:19843034-Postoperative Complications,
pubmed-meshheading:19843034-Systole,
pubmed-meshheading:19843034-Transplantation, Homologous,
pubmed-meshheading:19843034-Young Adult
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Strain-encoded cardiac magnetic resonance for the evaluation of chronic allograft vasculopathy in transplant recipients.
|
| pubmed:affiliation |
Department of Cardiology, University of Heidelberg, Heidelberg, Germany. gkorosoglou@hotmail.com
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| pubmed:publicationType |
Journal Article,
Controlled Clinical Trial
|