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pubmed-article:19833115pubmed:abstractTextAlpha 2 adrenergic receptors (alpha2 ARs) play a central role in the regulation of systemic sympathetic activity. Prejunctional alpha 2A adrenoceptor regulates through negative feedback at presynaptic nerve ending. A-1291 C>G polymorphism located in alpha2-adrenergic receptor gene (ADRAlpha2A) has been identified. We investigated the possible association between 1291 C>G polymorphism in the promoter region of ADRAlpha2A in clinical subtypes of IBS, ulcerative and microscopic colitis patients.lld:pubmed
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pubmed-article:19833115pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:19833115pubmed:articleTitleAssociation of alpha 2A adrenergic receptor gene (ADRAlpha2A) polymorphism with irritable bowel syndrome, microscopic and ulcerative colitis.lld:pubmed
pubmed-article:19833115pubmed:affiliationDepartment of Super Specialty Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.lld:pubmed
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