Linked Life Data

19823733

Source:http://linkedlifedata.com/resource/pubmed/id/19823733

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
21
pubmed:dateCreated
2009-10-13
pubmed:abstractText
We report a contraction-expansion array (CEA) microchannel that allows three-dimensional hydrodynamic focusing with a single sheath flow in a single-layer device. The CEA microchannel exploits centrifugal forces acting on fluids travelling along the contraction and expansion regions of the microchannel. Around an entrance of the contraction region, the centrifugal forces induce a secondary flow field where two counter-rotating vortices enable to envelop a sample flow with a sheath flow in three dimensions. We herein describe an underlying principle and a design of the CEA microchannel and demonstrate complete sheathing of a sample fluid (water and human red blood cells) in three dimensions. The focusing characteristics of the CEA microchannel are investigated in terms of the number of the rectangular structures, flow rate, and flow ratio between sample and sheath flows. This microfluidic channel for three-dimensional hydrodynamic focusing is easy to fabricate in a single-layer fabrication process and simple to operate with a single sheath flow.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1473-0197
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3155-60
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Three-dimensional hydrodynamic focusing with a single sheath flow in a single-layer microfluidic device.
pubmed:affiliation
Department of Bio and Brain Engineering, College of Life Science and Bioengineering, KAIST, 335 Gwahangno, Yuseong-gu, Daejeon 305-701, Republic of Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't