Source:http://linkedlifedata.com/resource/pubmed/id/19801953
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2009-11-25
|
pubmed:abstractText |
Phosphaturic mesenchymal tumor is an extremely rare disease and is frequently associated with oncogenic osteomalacia showing paraneoplastic syndrome, which is characterized by phosphaturia, hypophosphatemia, normocalcemia, and decreased levels of 1,25-dihydroxyvitamin D3 associated with a tumor. A 2-year-old boy, who had a soft tissue tumor on his right thigh and previously diagnosed as myositis ossificans at 9-months-old, was presented with rachitic rosary and mildly enlarged tumor. Biochemical investigations showed hypophosphatemia, hyperphosphaturia, and an increased alkaline phosphatase level of 440 U/l (25-100 U/l), suggesting rickets, which was resistant to vitamin D dietary supplementation. We were certain of intractable rickets because of oncogenic hypophosphatemia and thus decided to excise the soft tissue mass. We observed laboratory improvement of rickets after 2 weeks. On the basis of surgical and histopathological examinations, the tumor was finally diagnosed as the phosphaturic mesenchymal tumor.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1473-5865
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
127-32
|
pubmed:dateRevised |
2011-10-14
|
pubmed:meshHeading |
pubmed-meshheading:19801953-Alkaline Phosphatase,
pubmed-meshheading:19801953-Child, Preschool,
pubmed-meshheading:19801953-Diagnosis, Differential,
pubmed-meshheading:19801953-Humans,
pubmed-meshheading:19801953-Hypophosphatemia, Familial,
pubmed-meshheading:19801953-Hypophosphatemic Rickets, X-Linked Dominant,
pubmed-meshheading:19801953-Infant,
pubmed-meshheading:19801953-Male,
pubmed-meshheading:19801953-Mesenchymoma,
pubmed-meshheading:19801953-Myositis Ossificans,
pubmed-meshheading:19801953-Radiography, Thoracic,
pubmed-meshheading:19801953-Soft Tissue Neoplasms,
pubmed-meshheading:19801953-Thigh,
pubmed-meshheading:19801953-Treatment Outcome
|
pubmed:year |
2010
|
pubmed:articleTitle |
A 9-month-old phosphaturic mesenchymal tumor mimicking the intractable rickets.
|
pubmed:affiliation |
Departments of Orthopaedic Surgery, Gospel Hospital, Kosin University, Seogu, Busan, Korea.
|
pubmed:publicationType |
Journal Article,
Case Reports
|