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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
24
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pubmed:dateCreated |
2009-12-16
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pubmed:abstractText |
We assessed whether a single intracoronary infusion of autologous bone marrow cells (BMCs) can have a sustained impact on left ventricular ejection fraction (LVEF) in patients after ST-elevation myocardial infarction (STEMI). In the BOne marrOw transfer to enhance ST-elevation infarct regeneration (BOOST) trial, 60 patients with STEMI and successful percutaneous coronary intervention were randomized to a control and a cell therapy group. As previously reported, BMC transfer led to an improvement of LVEF by 6.0% at 6 months (P = 0.003) and 2.8% at 18 months (P = 0.27).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1522-9645
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pubmed:author |
pubmed-author:ArsenievLubomirL,
pubmed-author:DrexlerHelmutH,
pubmed-author:FichtnerStephanieS,
pubmed-author:GanserArnoldA,
pubmed-author:HahnAndreasA,
pubmed-author:LippoltPeterP,
pubmed-author:LotzJoachimJ,
pubmed-author:MeyerGerd PGP,
pubmed-author:PirrJensJ,
pubmed-author:RagerUlrikeU,
pubmed-author:SchaeferArndA,
pubmed-author:WollertKai CKC
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2978-84
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pubmed:meshHeading |
pubmed-meshheading:19773226-Adult,
pubmed-meshheading:19773226-Aged,
pubmed-meshheading:19773226-Bone Marrow Transplantation,
pubmed-meshheading:19773226-Follow-Up Studies,
pubmed-meshheading:19773226-Humans,
pubmed-meshheading:19773226-Magnetic Resonance Angiography,
pubmed-meshheading:19773226-Middle Aged,
pubmed-meshheading:19773226-Myocardial Infarction,
pubmed-meshheading:19773226-Stroke Volume,
pubmed-meshheading:19773226-Transplantation, Autologous,
pubmed-meshheading:19773226-Treatment Outcome,
pubmed-meshheading:19773226-Ventricular Dysfunction, Left
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pubmed:year |
2009
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pubmed:articleTitle |
Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial.
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pubmed:affiliation |
Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. meyer.gerdp@mh-hannover.de
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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