Source:http://linkedlifedata.com/resource/pubmed/id/19722549
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19
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pubmed:dateCreated |
2009-9-24
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pubmed:abstractText |
A new fluorescent probe for monitoring Zn(2+) was synthesized based on the structure of 7-hydroxyquinoline. Compared with 8-substituted quinolines, the new probe exhibited higher selectivity for Zn(2+) over Cd(2+). Its fluorescence enhancement (14-fold) and nanomolar range sensitivity (K(d) = 0.117 nM) were favorable toward biological applications. Experiments also showed that a cell-permeable derivative of the new probe was potentially useful for two-photon imaging in living cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1523-7052
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4426-9
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pubmed:meshHeading |
pubmed-meshheading:19722549-Cell Line, Tumor,
pubmed-meshheading:19722549-Crystallography, X-Ray,
pubmed-meshheading:19722549-Fluorescence,
pubmed-meshheading:19722549-Fluorescent Dyes,
pubmed-meshheading:19722549-Humans,
pubmed-meshheading:19722549-Hydroxyquinolines,
pubmed-meshheading:19722549-Models, Molecular,
pubmed-meshheading:19722549-Organometallic Compounds,
pubmed-meshheading:19722549-Photons,
pubmed-meshheading:19722549-Zinc
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pubmed:year |
2009
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pubmed:articleTitle |
Two-photon fluorescent probes of biological Zn(II) derived from 7-hydroxyquinoline.
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pubmed:affiliation |
Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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