|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0006864,
umls-concept:C0007595,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0027651,
umls-concept:C0033572,
umls-concept:C0086418,
umls-concept:C0256632,
umls-concept:C1314939,
umls-concept:C1413555,
umls-concept:C2677316
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2009-9-9
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|
pubmed:abstractText |
We have previously shown that cannabinoids induce growth inhibition and apoptosis in prostate cancer PC-3 cells, which express high levels of cannabinoid receptor types 1 and 2 (CB(1) and CB(2)). In this study, we investigated the role of CB(2) receptor in the anti-proliferative action of cannabinoids and the signal transduction triggered by receptor ligation.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1532-1827
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:day |
15
|
|
pubmed:volume |
101
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
940-50
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pubmed:dateRevised |
2010-9-16
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pubmed:meshHeading |
pubmed-meshheading:19690545-Animals,
pubmed-meshheading:19690545-Apoptosis,
pubmed-meshheading:19690545-Arachidonic Acids,
pubmed-meshheading:19690545-Cell Line, Tumor,
pubmed-meshheading:19690545-Cell Proliferation,
pubmed-meshheading:19690545-Ceramides,
pubmed-meshheading:19690545-Humans,
pubmed-meshheading:19690545-Indoles,
pubmed-meshheading:19690545-Male,
pubmed-meshheading:19690545-Mice,
pubmed-meshheading:19690545-Prostatic Neoplasms,
pubmed-meshheading:19690545-Receptor, Cannabinoid, CB2,
pubmed-meshheading:19690545-Signal Transduction,
pubmed-meshheading:19690545-Xenograft Model Antitumor Assays
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2.
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|
pubmed:affiliation |
Department of Biochemistry and Molecular Biology, School of Medicine, University of Alcalá, Alcalá de Henares, 28871 Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
